Chemistry was the focus of a recent project at Cycorp and therefore Cyc's representation of chemistry is more full than other parts of the ontology. Cyc has some competence in several different specializations of Chemistry, including the following:

• Analytical Chemistry, the science of making quantitative measurements of properties of chemical compounds. It employs techniques like mass spectrometry, electromagnetic radiation spectroscopy, titration, and gravimetric analysis.
• Bioanalytical Chemistry, analytical chemistry restricted to chemical substances found in living things.
• Computational Chemistry, the application of computer modelling techniques to problems in chemistry.
• Electrochemistry, the study of the movement and separation of charge in matter. As such, it is the study of the transfer of electrons. It has a number of applications in Analytical Chemistry.
• Environmental Chemistry, essentially the application of chemistry to the diagnosis of and solution to environmental problems. It deals with such things as the analysis of toxins in samples and the explanation of ozone holes and global warming.